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For best results, swallow 2 capsules per day with water 30 minutes away from an evening meal or as directed by your health care professional.
Ingredients
Growth Blend 677 A growth hormone secretagogue that stimulates natural GH and IGF-1 production. Supports muscle growth, recovery, bone density, and deep sleep quality.
Dihydroberberine A highly bioavailable form of berberine that supports healthy glucose metabolism, insulin sensitivity, and metabolic function with superior absorption.
Taurine A conditionally essential amino acid that supports cellular hydration, electrolyte balance, muscle function, and promotes a calm, focused state.
Magnesium Glycinate A highly absorbable form of magnesium that supports ATP energy production, healthy muscle contraction, relaxation, and restorative sleep.
Potassium Citrate An essential electrolyte mineral that supports proper muscle function, cellular hydration, and optimal energy production throughout the body.
AstraGin™ A patented blend of Astragalus membranaceus and Panax notoginseng shown to enhance nutrient absorption and support healthy gut function.
Key Questions Answered
Is this product legal and FDA-approved? MK-677 is not FDA-approved for human consumption and is classified as a research compound. However, it is legal to sell and purchase as a dietary supplement ingredient in the United States. Our product is formulated as a dietary supplement and is manufactured in FDA-registered, GMP-certified facilities with third-party testing for purity and potency.
Will this cause blood sugar problems? MK-677 alone can temporarily elevate fasting blood glucose in some users. However, Optimum MK-677 is specifically formulated with Dihydroberberine, a highly bioavailable compound that enhances insulin sensitivity and supports healthy glucose metabolism. This synergistic combination is designed to help maintain balanced blood sugar levels while you experience the benefits of growth hormone optimization. If you have diabetes or pre-diabetes, consult your healthcare provider before use.
How does Dihydroberberine protect against blood sugar issues? Dihydroberberine activates AMPK (your body's metabolic master switch), which enhances insulin sensitivity and helps cells absorb glucose more efficiently. It's up to 5x more bioavailable than regular berberine and works to counterbalance MK-677's potential effects on blood sugar. This intelligent formulation allows you to experience growth hormone benefits while supporting healthy metabolic function.
Will I experience water retention or bloating? Some users may experience mild, temporary water retention, particularly in the first 2-3 weeks. However, Optimum MK-677 includes Potassium Citrate, Taurine, and Magnesium Glycinate specifically to support healthy fluid balance and minimize bloating. Staying well-hydrated (2.5+ liters daily) and maintaining adequate potassium intake (which our formula provides) significantly reduces water retention concerns.
Will this make me hungrier? MK-677 mimics ghrelin (the hunger hormone), which can increase appetite in some users. This effect is typically most noticeable in the first 2-3 weeks and often subsides as your body adapts. Many users find this beneficial during muscle-building phases. If appetite increase is unwanted, taking your dose in the evening rather than morning may help.
How long until I see results? Most users report improved sleep quality within 3-7 days. Noticeable improvements in recovery, skin quality, and well-being typically appear within 2-3 weeks. Muscle growth, body composition changes, and bone density improvements become more apparent after 8-12 weeks of consistent use. Growth hormone optimization is a gradual process that compounds over time.
Is this safe for long-term use? Our formula is designed for cyclical use. We recommend 12-16 week cycles followed by 4-6 week breaks to allow your body's natural hormone production to maintain balance. Regular monitoring through blood work (fasting glucose, HbA1c, IGF-1) is advised for extended use. Always consult with a healthcare provider for personalized guidance.
Can I take this if I have diabetes or insulin resistance? If you have diabetes, pre-diabetes, or known insulin resistance, consult your healthcare provider before use. While our Dihydroberberine content supports healthy glucose metabolism, medical supervision is essential. Monitor your blood glucose more frequently when starting, and be aware that dosage adjustments to diabetes medications may be necessary.
Will this interact with my medications? MK-677 and Dihydroberberine can interact with certain medications, particularly diabetes drugs (metformin, insulin), blood pressure medications, and blood thinners. Magnesium can affect absorption of certain antibiotics and thyroid medications. Always consult your healthcare provider before combining with prescription medications, and separate doses by at least 2 hours when possible.
What if it doesn't work for me? Results can vary based on individual factors including age, baseline hormone levels, diet, training, and sleep quality. Growth hormone optimization works best when combined with proper nutrition, regular exercise, and adequate sleep. If you're not satisfied with your results, we offer a 30-day money-back guarantee. Many users find optimal results after 8-12 weeks of consistent use.
Can I take this if I have heart problems? If you have any history of heart disease, heart failure, high blood pressure, or other cardiovascular conditions, consult your healthcare provider before use. MK-677 can cause fluid retention which may affect blood pressure in some individuals. Medical supervision is advised for anyone with cardiovascular concerns.
How should I take this product? Take 2 capsules once daily, preferably in the evening on an empty stomach or with a light meal. Taking at night may enhance sleep quality and reduce daytime appetite effects. For best results, maintain consistent daily use and stay well-hydrated throughout the day.
Is this third-party tested? Yes, every batch of Optimum MK-677 undergoes rigorous third-party laboratory testing for purity, potency, and contaminants. We test for heavy metals, microbiological contaminants, and verify active ingredient concentrations. Certificates of Analysis are available upon request.
Risk Free Guarantee
We offer a 30-day money back guarantee on Optimum MK-677! Achieve your best with our MK-677 or your money back! See our Return Policy
The Ultimate Growth Hormone Solution for Performance & Recovery
Muscle Growth & Strength
Stimulates natural GH and IGF-1 release, activating muscle protein synthesis for increased lean mass, strength, and faster recovery between workouts.
Deep Sleep & Recovery
Enhances REM and deep sleep duration for superior overnight recovery, improved cognitive function, and optimized muscle repair.
Body Recomposition
Elevates metabolism and fat oxidation while preserving muscle. Enhanced insulin sensitivity and GLP-1 from Dihydroberberine supports improved body composition.
Bone Density & Joint Health
Increases bone mineral density and supports collagen synthesis in joints for improved mobility, flexibility, and long-term skeletal health.
Anti-Aging & Skin Health
Boosts collagen production and cellular regeneration for improved skin elasticity, reduced fine lines, and a more youthful appearance.
Cognitive Function & Mood
Enhances neurotransmitter balance and neuroplasticity. Users report improved mental clarity, focus, elevated mood, and better stress management.
Clinically Backed by 300+ Studies
Explore studies
"Growth Blend Increases Growth Hormone"
Clinical research in both young men ages 18-30 and elderly subjects ages 64-81 demonstrates that daily oral Growth Blend administration significantly activates the GH-IGF-I axis across age groups, increasing plasma IGF-I levels in a dose-dependent manner while maintaining pulsatile GH release without affecting cortisol levels.
"Growth Blend Increases Lean Muscle Mass"
A 2-month placebo-controlled trial in obese males showed that daily Growth Blend treatment significantly increased fat-free mass by 3kg compared to placebo, while transiently elevating basal metabolic rate by 10% and increasing 24-hour energy expenditure.
"Growth Blend Increases Deep Sleep Levels"
Double-blind, placebo-controlled studies show that prolonged Growth Blend treatment produces approximately 50% increase in stage IV deep sleep duration and over 20% increase in REM sleep in both young and elderly subjects, while reducing sleep abnormalities from 42% to 8%.
"Growth Blend Increases Bone Formation"
Controlled studies in 187 elderly adults (ages 65+) demonstrate that Growth Blend significantly increases markers of bone formation and turnover in both healthy and functionally impaired subjects, with osteocalcin levels rising 39-45% within 6-8 weeks of daily treatment.
"Growth Blend Reverses Muscle Wasting"
Clinical trials demonstrate that Growth Blend completely reverses nitrogen wasting caused by caloric restriction, shifting nitrogen balance from -1.48g/day (placebo) to +0.31g/day (p<0.016), indicating powerful anti-catabolic effects and muscle preservation during dieting.
Results that Speak for Themselves
Enhanced Muscle & Recovery
➤ Increased Lean Mass ➤ Accelerated Recovery ➤ Preserved Muscle
➤ Elevated Metabolism ➤ Improved Bone Density ➤ Youthful Skin Health
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One or more of the items in your cart is a recurring or deferred purchase. By continuing, I agree to the cancellation policy and authorize you to charge my payment method at the prices, frequency and dates listed on this page until my order is fulfilled or I cancel, if permitted.
One or more of the items in your cart is a recurring or deferred purchase. By continuing, I agree to the cancellation policy and authorize you to charge my payment method at the prices, frequency and dates listed on this page until my order is fulfilled or I cancel, if permitted.
